• Also known as shipping fever, stockyard pneumonia, septicemic pasteurellosis
• Acute infectious respiratory disease of cattle, buffalo, sheep and pig
• Characterized by Septicemia (Blood poisoning by bacteria), fever, sign of bronchopneumonia and a high mortality rate.
• Animal of all age group are susceptible.

a) Etiology:

• Pasteurulla multocida

b) Transmission:

• Through carrier animal
• Organism localizes in nasopharyngeal mucosa and tonsils
• Spread in environment by

i) nasal discharge, saliva, milk and faeces of sick animal

ii) Inhalation of infected fomites or droplets

iii) Ingestion of contaminated feed

iv) Bite of blood sucking ectoparasites

c) Pathogenesis:

• Inhabit to tonsils and nasopharangeal mucosa à Multiply and reaches alveoli à Bacteria produce endotoxin à Produce proteolytic enzymes à lysis of cell membrane à increases cell permeability à fluid accumulation in interstitial space of alveolar wall à pulmonary edemaà necrosis of alveolar wall

d) Signs and symptoms:

• Fever ( 106-107⁰F), dullness and reluctance to move.
• Excessive salivation, profuse serous nasal discharge
• Broncho-pneumonia, coughing
• Severe dyspnea, with frothing at the mouth
• Sub-mandibular edematous swelling
• Inflamed tongue, Asphyxia, Death within 12-48 hrs.

e) Diagnosis:

• High fever, swelling of throat region
• Haemorrhages throughout the body
• Bacterial examination from heart blood and spleen.

f) Control:

• Vaccination before rainy season

g) Differential diagnosis:

• Anthrax, Black leg, Rinderpest, Acute poisoning, etc.