• Also known as Bang’s disease in animal and malta fever in human.
• Highly contagious disease of cattle, camel , sheep, goat and swine
• Characterized by inflammation of genital organs and fetal membrane, abortion with retained placenta.

a) Etiology:

• Brucella abortus , B. ovis , B. susi, B. canis, etc.

b) Transmission:

• Content of pregnant uterus, Fetus, Fetal membrane, urine, milk, semen, faeces, etc.

c) Pathogenesis:

• Entry of pathogen by ingestion à Enter and travel through intestinal walls à enter into lymphatics à localize in regional nodes and proliferate à Enter into lymphatics and reach blood vessels à localization in variety of tissue à in uterus, spleen, udder, lungs, spleen, etc.

d) Symptoms:

• High incidence of abortion
• Retention of placenta
• Birth of death calves
• Infertility and sterility
• Inflammation of testes

e) Diagnosis:

• Clinical signs and symptoms
• Allergic test
• Isolation and identification of organism
• Bacterial culture
• Milk ring test
• Serological test